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Ubayd Ali

Authored by

Ubayd Ali

Superintendent Pharmacist

Registration Number: 2219322

NHS Pharmacist and founding member of HEBA, with years of experience in healthcare across innovative organisations.
Sufyan Tahir

Reviewed by

Sufyan Tahir

Clinical Governance Lead

Registration Number: 2221275

Review Date 3 April 2026
Next Review 3 April 2028
Published on 3 April 2026
Last Update 3 April 2026

Description

Co-codamol tablets combine two active ingredients to provide effective relief from moderate pain. The paracetamol works to reduce pain and fever, while codeine is an opioid analgesic that enhances the overall pain-relieving effect. Co-codamol tablets are typically recommended when ibuprofen or paracetamol alone have not provided sufficient relief. Because they contain codeine, Co-codamol tablets should be used with caution and only for short durations.

  • Contains paracetamol and codeine
  • Provides relief from moderate pain
  • Suitable for headaches, dental pain and muscular aches
  • Intended for short-term use only

Directions

Take Co-codamol tablets exactly as directed on the packaging or as advised by a healthcare professional. The usual adult dose is one or two Co-codamol tablets every four to six hours as needed, without exceeding the maximum daily dose stated on the label. Swallow Co-codamol tablets whole with water. Do not take Co-codamol tablets for more than three consecutive days without medical advice, as prolonged use may lead to dependence.

Ingredients

Co-codamol tablets contain paracetamol and codeine phosphate as the active ingredients, commonly available in strengths such as 8mg codeine with 500mg paracetamol, though other strengths may exist. Inactive ingredients may include starch, povidone and magnesium stearate to help form and stabilise the tablet.

The exact formulation and strength of Co-codamol tablets are listed on the packaging and patient information leaflet. Always check the ingredients if you have allergies or sensitivities.

Warnings

Do not take Co-codamol tablets if you are allergic to paracetamol, codeine or any of the listed ingredients. Co-codamol tablets may cause drowsiness, dizziness or constipation, and you should avoid driving or operating machinery if affected.

Do not take Co-codamol tablets with other products containing paracetamol, as this can lead to serious liver damage.

Consult a doctor before using Co-codamol tablets if you are pregnant, breastfeeding, have breathing problems or a history of substance misuse, and keep out of reach of children.
 
 
 

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Frequently asked questions

  • What are Co-Codamol Tablets used for?

    Co-Codamol Tablets are used to relieve moderate pain that is not effectively managed by paracetamol or ibuprofen alone. They combine two pain-relieving ingredients to provide stronger relief for short-term conditions such as dental pain, headaches, or muscle aches.

     

  • How do Co-Codamol Tablets work in the body?

    Co-Codamol Tablets contain paracetamol and codeine, which work together to reduce pain signals. Paracetamol eases pain and fever, while codeine acts on the brain and nervous system to enhance pain relief.

     

  • Can Co-Codamol Tablets cause drowsiness?

    Yes, Co-Codamol Tablets may cause drowsiness because of the codeine component. It is important to avoid driving or operating machinery if you feel sleepy or less alert after taking them.

     

  • Are Co-Codamol Tablets suitable for long-term use?

    Co-Codamol Tablets are generally recommended for short-term use only due to the risk of dependence associated with codeine. Prolonged use should only occur under medical supervision.

     

  • Can Co-Codamol Tablets be taken with other medicines?

    Co-Codamol Tablets may interact with certain medications, especially other products containing paracetamol or sedatives. Always check with a healthcare professional or pharmacist before combining them with other treatments.
     
     
     

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