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Ubayd Ali

Authored by

Ubayd Ali

Superintendent Pharmacist

Registration Number: 2219322

NHS Pharmacist and founding member of HEBA, with years of experience in healthcare across innovative organisations.
Sufyan Tahir

Reviewed by

Sufyan Tahir

Clinical Governance Lead

Registration Number: 2221275

Review Date 30 April 2026
Next Review 30 May 2028
Published on 30 April 2026
Last Update 30 April 2026

Tadalafil is used to treat erectile dysfunction in men.

Tadalafil is now available in a lower dose especially formulated for once daily use. Tadalafil 2.5mg and 5mg tablets can be taken every day to allow for more spontaneous erections. You no longer need to worry about having to take Tadalafil tablets to coincide with sex.

You can buy Tadalafil once-daily tablets in two versions, the branded version called Cialis once daily and the non-branded version called Tadalafil once daily. The only difference is when you buy Tadalafil once daily it will be much cheaper but will work in the exact same way by allowing an erection. These tablets are one of many Erectile Dysfunction medications that can help increase blood flow to the penis, and this specific medication is designed for daily use and allows for spontaneous erections.

Take a Tadalafil once a day at the same time, the medication will remain effective for as long as you are taking it. Do not take more than 1 tablet a day, this treatment is intended for continuous use. Erectile dysfunction can cause problems such as low self-esteem, stress and even depression, so it’s important to always consult your doctor/prescriber if you have any questi

If you buy these tablets you should always take the medication exactly as your doctor has prescribed. Normally these tablets are taken once each day at the same time of day. Check with your doctor or pharmacist if you are not sure.These tablets should be swallowed whole with some water and are able to be taken with or without food. Do not take more than one tablet a day, remember you will still need sexual stimulation to gain an erection.

Side Effects
Common side effects of Tadalafil use include:

  • Headache
  • Muscle aches
  • Facial flushing
  • Nasal congestion
  • Indigestion

 

These are temporary and tend to disappear within a few hours.

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Frequently asked questions

  • How effective is Tadalafil

    Tadalafil works for most men with erectile dysfunction — around 7 or 8 in 10 find it effective.

    Take it 30–60 minutes before sex. It lasts around 4–6 hours. Sexual arousal is still needed for it to work.

    Don't take it if you use nitrate medicines (e.g. GTN spray) — speak to your pharmacist or GP first if you're unsure.

  • How quickly does Tadalafil work?

    Tadalafil usually starts working within 30–60 minutes.

    It lasts much longer than other ED tablets — up to 36 hours — which is why it's sometimes called the "weekend pill."

  • What is the difference between Tadalafil and Cialis?

    Tadalafil is the generic form of Cialis. They are essentially the same treatment sold under a different name. Cialis is a well-known brand and therefore more expensive than the generic equivalent. In terms of ingredients and effectiveness, however, they are identical.

  • Can I take Tadalafil with other medicines?

    You should not take Tadalafil with other medications unless your doctor or pharmacist has told you that it is safe to do so. Sildenafil can interact with other medications, especially nitrates used in the treatment of chest pains and may result in a dangerously low drop in blood pressure.

  • What if Tadalafil doesn't work the first time?

    If Tadalafil doesn't work for you the first time it may be because:

    • you have not waited long enough for it to get to work before attempting to have see
    • you have waited too long after taking it
    • the dose was not high enough for your needs
    • you were not sufficiently sexually aroused

    States of anxiety and stress can prevent sexual arousal and may therefore make Tadalafil less effective. It is still important to be aroused and as relaxed as possible

  • Will Tadalafil affect my fertility?

    No. There is no clear evidence stating that Tadalafil affects the fertility of men who take it.

  • How long can I take Tadalafil for?

    Tadalafil is safe to take in the long term. There is no evidence to suggest that taking Tadalafil in accordance with dosage guidelines has any negative effects over the span of many months or even years.

  • What's the difference between the different strengths?

    The different strengths of Tadalafil Once daily tablets (2.5mg, 5mg) refer to the amount of the active ingredient present in each tablet. 2.5mg is a common starting dose for most men with ED, and this may be increased depending on your needs.

  • Are there any alternatives to Tadalafill?

    There are several alternatives to Tadalafil ranging from alternative medications to non-medical alternatives.

    Medical alternatives include the generic medications Sildenafil (often sold under the brand name Viagra) and Vardenafil (often sold under the brand name (Levitra).

    These are also PDE5 inhibitors and work in the same ways.

    Other non-medical alternatives include penis pumps that use suction to draw blood flow to the penis, or penile rings that inhibit the flow of blood away from the penis for longer-lasting erections.

  • How do I buy Tadalafil tablets online?

    It's quick and easy to make sure that Tadalafil is the right ED treatment for you, before deciding on a dosage that best fits your needs.

    A short online consultation is needed to make sure that this treatment is a good fit for you. This process is quick, easy and completely confidential.

    Once we have determined that SIldenafil is a safe and appropriate ED treatment for you, the product can be made available.

    Always consult with a licensed medical professional before starting any new treatment.

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